The task has been used to assess cognitive function, motivation, brain and spinal cord injury and disease consequences and work/reward relations in animals and as a therapy and exercise tool in humans.
Variations of the behavior are observed in over 160 species of animals including birds, bees, rodents and primates and humans ( Jacobs and Osvath, 2015 Singh et al., 2019). String-pulling is a proto-tool behavior in which an animal pulls on a string to obtain a reward.
Head injury video fractal software#
The utility of the task and software is demonstrated by characterizing postural and hand kinematic differences in string-pulling behavior of two strains of mice, C57BL/6 and Swiss Webster. Based on image-segmentation and heuristic algorithms for object tracking, the software also allows tracking of body, ears, nose, and forehands for estimation of kinematic parameters such as body length, body angle, head roll, head yaw, head pitch, and path and speed of hand movements. Here, we describe a Matlab-based software that allows whole-body motion characterization using optical flow estimation, descriptive statistics, principal component, and independent component analyses as well as temporal measures of Fano factor, entropy, and Higuchi fractal dimension.
Typical analysis includes kinematic assessment of hand movements done by manually annotating frames. String-pulling by rodents is a behavior in which animals make rhythmical body, head, and bilateral forearm as well as skilled hand movements to spontaneously reel in a string.
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